Common Side Effects is an American adult animated television series created by Joe Bennett and Steve Hely for Cartoon Network‘s nighttime programming block Adult Swim. It was produced by Bandera Entertainment, with key crew members of King of the Hill involved in production.
Two high school friends, Marshall and Frances, reconnect after Marshall discovers the Blue Angel Mushroom, a mushroom with healing effects that appears to cure all illnesses. In the process, they also uncover a conspiracy involving Reutical Pharmaceuticals, Inc., one of the largest pharmaceutical companies, and the government, to suppress all knowledge of said mushroom.[2]